http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102964345-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-10 |
| filingDate | 2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102964345-B |
| titleOfInvention | A kind of preparation method of 2-hydroxyl-2,2-diphenyl acetic acid-3 α-(8-azabicyclo [3,2,1])-3-monooctyl ester |
| abstract | The invention discloses the preparation method of a kind of 2 hydroxyl 2,2 diphenyl acetic acid 3 α (8 azabicyclos [3,2,1]) 3 monooctyl esters.This method is with dibenzoyl as raw material; rearranged obtain dibenzene-hydroxy-acetic acid; under DBU catalysis and microwave action, obtain dibenzene-hydroxy-acetic acid methyl ester with dimethyl carbonate effect, then react with tropanol and obtain diphenylhydroxy acetic acid tropine ester, then obtain the nor-tropeine of dibenzene-hydroxy-acetic acid through N formylated and alcoholysis.The total reaction time of the method has relative to prior art and significantly reduces, and total recovery is greatly improved, and reaction condition is simpler, it is adaptable to industrialized production. |
| priorityDate | 2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.