http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102958938-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c106c45f14d545d46d15dce51241db48 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5146 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
filingDate | 2011-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c667405ec365a03fdd7a39e53e41b0c8 |
publicationDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102958938-B |
titleOfInvention | Enzyme-degradable polymer and application thereof |
abstract | The present invention belongs to the biomedicine field and specifically concerns an enzyme-degradable polymer and application thereof. To solve the problem of low sensitivity of the existing assay reagents, the present invention provides an enzyme-degradable polymer and the related application of the polymer. The present invention also provides hydrogels, nano-particles, fluorescent dye-labeled enzyme substrates and kits (packages) for detection or activity-analysis of biological enzymes based on the enzyme-degradable polymer. The formula of the enzyme-degradable polymer is P1-(aa)N-(AA)n-X, wherein, (aa)N is a non-enzyme substrate domain, the N aa may be different (no correlation), and N is a non-negative integer. (AA)n is an enzyme substrate domain, the n AA may be different, and N is a non-negative integer. P1 is a protecting group of alpha-amino or functional group, P2 is a protecting group of alpha-amino, and P3 is -NH2, a small molecule compound or a fragment of a polymer. |
priorityDate | 2011-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 154.