http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102952281-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2399eb88402d63c396319544918b4c2 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K3-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K5-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 |
| filingDate | 2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf4eb2f6af203f162709248ab0c0f4dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_953329adda0fe9f62d9a463c006aa45b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7968cbb8c91a8085454fa2bed8277543 |
| publicationDate | 2014-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102952281-B |
| titleOfInvention | Preparation method of chitosan oligosaccharide and hyaluronic acid cross-linked gel |
| abstract | The invention discloses a preparation method of chitosan oligosaccharide and hyaluronic acid cross-linked gel. The hyaluronic acid and chitosan oligosaccharide composite gel is prepared by using a 1-ethyl-(3-dimethyllaminopropyl) carbodiimide hydrochloride cross-linking agent under a neutral condition so that the problem of acid degradation of hyaluronic acid is avoided, and the carboxyl of hyaluronic acid and the amino of chitosan oligosaccharide are promoted to react to form gel; and after the reaction is ended, the cross-linking agent can be thoroughly removed from hyaluronic acid and chitosan oligosaccharide composite gel through simple washing, so that the purity of hyaluronic acid and chitosan oligosaccharide composite gel is ensured. The hyaluronic acid and chitosan oligosaccharide composite gel prepared according to the invention simultaneously has the excellent biocompatibility of hyaluronic acid and the special protection function of chitosan oligosaccharide to cells and is convenient and flexible to use and higher in practical value. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11780970-B2 |
| priorityDate | 2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.