abstract |
The present invention relates to the field of medicinal chemistry, in particular to estrogen derivatives of general formula (I), their pharmaceutically acceptable salts, their preparation methods and their medical uses, the compounds of the present invention and their pharmaceutically acceptable The salt is used for the treatment of pathological angiogenesis-related diseases such as tumors, retinopathy, rheumatoid arthritis, diabetes, lupus erythematosus, chronic inflammatory reactions and the like. For the definition of each group in the formula, see the description for details. |