http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102952057-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-267 |
filingDate | 2012-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102952057-B |
titleOfInvention | A kind of preparation method of 4-isobutyl-pyrrolidin-2-one |
abstract | The present invention relates to the preparation method of pregabalin intermediate 4-isobutyl-pyrrolidin-2-one, belong to field of medicine and chemical technology.The present invention for raw material with 3-cyano group-5-methylhexanoic acid ester, in the organic solvent containing ammonia and/or organic amine, carries out hydrogenation in the presence of a catalyst, obtains 4-isobutyl-pyrrolidin-2-one.The method raw material is easy to get, easy and simple to handle, and production cost is low, and transformation efficiency is high, and plant factor is high, environmentally friendly, is applicable to industrialized production. |
priorityDate | 2012-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.