http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102949351-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c17bfd6a5ee59ba0191317bc9ff813f6
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4188
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19
filingDate 2011-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c058ea89b206b075cf1059307c635fae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ff02201eec21829e2a29ee7d30875bc
publicationDate 2015-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102949351-B
titleOfInvention Preparation method of temozolomide lyophilized preparation
abstract The invention discloses a preparation method of a temozolomide lyophilized powder preparation. The method includes: dissolving temozolomide or its pharmaceutically acceptable salt, a filler, and a pH regulator in a mixed solvent, conducting filtering, and then performing lyophilization, thus obtaining the temozolomide lyophilized powder preparation. Specifically, the mixed solvent is a tertiary butanol/water mixed system. The preparation method provided in the invention has the advantages of simple preparation process, convenience and feasibility, as well as good repeatability. As the preparation time and lyophilization time are shortened, the production cost can be reduced, thus generating tremendous economic benefits.
priorityDate 2011-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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