| abstract |
With hprl receptor antibody 005-C04 and mature form thereof in the present invention relates to, and Fab, comprise their pharmaceutical composition, and they in the benign conditions for the treatment of or the mediation of prevention hprl receptor and indication as the purposes in endometriosis, adenomyosis, non-hormone female contraception, benign breast disease and mazalgia, lactation suppression, benign prostatic hyperplasia, fibroma, hyperprolactinemia and the normal hypophosphatemic alopecia of prolactin, and in associating hormonotherapy Synergistic treatment to suppress the purposes in mammary epithelial cell proliferation.The intracellular signaling of antibody blocking hprl receptor mediation of the present invention. |