http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102942935-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_217f2be73fd6be0be36dd55803d3bec5 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-88 |
filingDate | 2012-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a72a8793c32c18dc974956b86c15c43c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef9adea8f00cee0a6d506c479a5dd4e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3427d72d6564bc8b5da01fe3bed57241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53a47b20e3e686df560dd1ae25954392 |
publicationDate | 2013-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102942935-B |
titleOfInvention | One-step method for synthesizing DNA functionalized Zn doped CdTe quantum dot |
abstract | The invention belongs to the fields of nanometer materials and biomedical analysis chemistry, and particularly relates to a one-step method for synthesizing DNA functionalized Zn doped CdTe quantum dots. The quantum dot probe is prepared by connecting phosphorylated DNA to surface of quantum dot by coordination of sulfur and cadmium, and quantum dot surface can be connected with 1-2 DNA fragments. The preparation method is as below: in a synthesis process of quantum dots, phosphorylated DNA is added to obtain the DNA functionalized quantum dot probe through a one-step reaction. The probe can be used as a bifunctional nanometer material, has high fluorescence quantum yield, good biocompatibility and good dispersion, and can be used for detection of DNA fragment and protein, cell identification and tumor targeting. Compared with a traditional DNA marked quantum dot method, the preparation method provided by the invention is simple and low-cost, does not require expensive preparation facilities, can be accomplished in general chemistry laboratory, and can be widely used in fields of biological detection, cellular imaging, target tracing and disease diagnosis, etc. |
priorityDate | 2012-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.