http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102942935-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_217f2be73fd6be0be36dd55803d3bec5
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-88
filingDate 2012-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a72a8793c32c18dc974956b86c15c43c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef9adea8f00cee0a6d506c479a5dd4e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3427d72d6564bc8b5da01fe3bed57241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53a47b20e3e686df560dd1ae25954392
publicationDate 2013-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102942935-B
titleOfInvention One-step method for synthesizing DNA functionalized Zn doped CdTe quantum dot
abstract The invention belongs to the fields of nanometer materials and biomedical analysis chemistry, and particularly relates to a one-step method for synthesizing DNA functionalized Zn doped CdTe quantum dots. The quantum dot probe is prepared by connecting phosphorylated DNA to surface of quantum dot by coordination of sulfur and cadmium, and quantum dot surface can be connected with 1-2 DNA fragments. The preparation method is as below: in a synthesis process of quantum dots, phosphorylated DNA is added to obtain the DNA functionalized quantum dot probe through a one-step reaction. The probe can be used as a bifunctional nanometer material, has high fluorescence quantum yield, good biocompatibility and good dispersion, and can be used for detection of DNA fragment and protein, cell identification and tumor targeting. Compared with a traditional DNA marked quantum dot method, the preparation method provided by the invention is simple and low-cost, does not require expensive preparation facilities, can be accomplished in general chemistry laboratory, and can be widely used in fields of biological detection, cellular imaging, target tracing and disease diagnosis, etc.
priorityDate 2012-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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