| abstract |
Provide C-3,11,12,20-tetrasubstituted C-21 steroid derivatives of general formula I and their pharmaceutically acceptable salts and glycosides, and a pharmaceutical composition using it as an active ingredient, which is used in the preparation of epilepsy application in disease medicine. In formula I: R 1 , R 2 , and R 3 are each independently a ketone group, a hydroxyl group, a substituted acyl ester group, an amino group, and a substituted amido group; R 4 is a keto group, a hydroxyl group, a substituted acyl ester group, an amino group, and a substituted amido group , sugar group; R 5 , R 6 , R 7 are each independently hydrogen, hydroxyl and its substituted acyl ester group, amino and substituted amido. |