http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102924499-B

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Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18
filingDate 2012-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102924499-B
titleOfInvention The synthesis of L-3,4,5-trioxy--phenylalanine/aldehyde cpd
abstract L-3 of the present invention; the synthesis of 4,5-trioxy--phenylalanine/aldehyde cpd, provides the L-3 of amino, phenolic hydroxyl group protection; 4; the preparation method of 5-trioxy--phenylalaninol (structural formula is as follows), and it is converted into efficiently the L-3 of protection, 4; 5-trioxy--phenylalanine/aldehyde; develop synthesis L-3, the novel method of 4,5-trioxy--phenylalanine/aldehyde cpd brief and practical.L-3,4,5-trioxy--phenylalanine structure is extensively present in and manyly has in the molecule of notable biological activity and function, L-3 simultaneously, does is 4,5-trioxy--phenylalanine/aldehyde cpd the Ecteinascidin that chiral synthesize has height antitumour activity? 743, Phthalascidin? 650, the very important intermediate of tetrahydroisoquinoline alkaloid such as Saframycin.Present method overcomes the some shortcomings in synthesis in the past, and have step short, productive rate is high, and raw material is cheap, easy and simple to handle, is easy to the advantages such as industrialization, is the good method of one of preparation L-3,4,5-trioxy--phenylalanine/aldehyde cpd.
priorityDate 2012-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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