http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102924499-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
| filingDate | 2012-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb99f61ad695adfd52f21c985f2a4c48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c78c11cd12504cdf1e9c084720f6f1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd3c987381a57b9c623125d8742da773 |
| publicationDate | 2013-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102924499-A |
| titleOfInvention | Synthesis of L-3,4,5-trioxo-phenylalanine/aldehyde compound |
| abstract | The synthesis of L-3,4,5-trioxo-phenylalanine/aldehyde compound of the present invention provides L-3,4,5-trioxo-phenylalaninol (structural formula) of amino group and phenolic hydroxyl protection as follows) and efficiently convert it into protected L-3,4,5-trioxo-phenylalanine/aldehyde, and develop the synthesis of L-3,4,5-trioxo-benzene A concise and practical new method for alanine/aldehyde compounds. The L-3,4,5-trioxo-phenylalanine structure widely exists in many molecules with significant biological activities and functions, while L-3,4,5-trioxo-phenylalanine/aldehyde The compound is a very important intermediate for the chiral synthesis of tetrahydroisoquinoline alkaloids such as Ecteinascidin743, Phthalascidin650 and Saframycin with high anticancer activity. This method overcomes some deficiencies in previous synthesis, and has the advantages of short steps, high yield, cheap raw materials, easy operation, and easy industrialization, etc. A great way to compound. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106588698-A |
| priorityDate | 2012-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.