| abstract |
The present invention relates to 6,6-bicyclic substituted heterobicyclic protein kinase inhibitors. The present invention discloses compounds of formula (I) and pharmaceutically acceptable salts thereof (wherein X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 , R 1 and Q 1 are as defined herein) to inhibit IGF-IR enzymes are also useful in the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, diseases and conditions of the immune system, diseases and conditions of the central nervous system. |