abstract |
The invention relates to a class of desloratadine derivatives and a preparation method and use thereof. Specifically, it relates to a class of desloratadine derivatives with the structure of formula I and pharmaceutically acceptable salts thereof and preparation methods thereof, desloratadine derivatives of the structure of formula I and pharmaceutically acceptable salts thereof Pharmaceutical composition as an active ingredient and its role in the prevention or treatment of arginine vasopressin V1a receptor, arginine vasopressin V1b receptor, arginine vasopressin V2 receptor, sympathetic nervous system or kidney Use in diseases related to the hormone-angiotensin-aldosterone system. |