http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102920963-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-904 |
filingDate | 2012-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102920963-B |
titleOfInvention | The preparation technology of acute and chronic pharyngitis medicine scale |
abstract | The invention discloses one and treat acute and chronic pharyngitis medicine large-scale preparation method, belong to the process modification of Yanyan slice.The present invention relates to preparation and preparation process condition two large divisions that scale-up process flow process comprises raw medicinal material, wherein the preparation of raw medicinal material comprise that crude drug is cleaned, drying, shave, draw down, sterilization and infiltration; Preparation process condition comprises extraction-stranding cream, pulverizing-granulation, drying-granulate, always mixed-tabletting-coating, and the respective conditions used in these technological processes.The object of the invention is to overcome effective one-tenth side content in existing tablet not high, during large-scale production, medicine stability is poor, the shortcoming such as between batch diversity is large.Adopt vapour-liquid separating phase transformation entirely to imitate column plate and platelet distance essence to slip tower by extracting, rub with the hands in cream, crushing process and adopt crawler type dry, granulate is always sneaked out Cheng Zhongke and is adopted three-dimensional motion mixing, and sweet tablet weightening finish in coating process, can be adopted to be 40 ~ 80%, the amount of gastric solubility film coating pre-mix dose is 2 ~ 3% process modification that substrate is heavy, improve the product yield of large-scale production medicine, add the stability of medicine, reduce production cost. |
priorityDate | 2012-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.