http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102911133-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47a6b69c9840f09afce6528cce19ff95 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-14 |
| filingDate | 2012-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42ccaba55294c7cfdb41270bcaedc70b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8365092244e9d17cc21e28f0ab04ec39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6261608dea50275f0f12a56f9da34b3c |
| publicationDate | 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102911133-B |
| titleOfInvention | Purification method of (4R,5R)-2- dichloromethyl-4,5- dihydro-5-(4-methylsulfonyl-phenyl)-4-oxazol methanol |
| abstract | The invention relates to a purification method of (4R,5R)-2- dichloromethyl-4,5- dihydro-5-(4-methylsulfonyl-phenyl)-4-oxazol methanol. The purification method includes steps of firstly, adding a certain quantity of alkyl alcohol and organic amine into wet crude product of the (4R,5R)-2-dichloromethyl-4,5-dihydro-5-(4-methylsulfonyl-phenyl)-4-oxazol methanol, heating to dissolve, stirring at the temperature of 45-75 DEG C, adding water slowly to precipitate crystals, cooling to be 0-20 DEG C, stirring for 1-3 hours, filtering and drying to obtain the purified product. The weight ratio of the wet crude product, the alkyl alcohol, the organic amine and water is equal to 1:(0.6-3):(0.002-0.02):(1.5-10), the wet crude product is metered by gram, and the alkyl alcohol, the organic amine and water are metered by milliliter. The purification method has good purification effect, products are high in quality, production in scale is facilitated, cost for raw materials is reduced, production cycle is shortened and energy consumption is reduced. |
| priorityDate | 2012-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.