| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_173bc2c63b34988699010ba05e5b1376 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-66 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C35-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-132
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-52 |
| filingDate |
2011-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_975070573a1ebb5fb2babfc38c409ecf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_395f07db429b618685a8e85acf52e6cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd446d8d0a4bd3ce5928d13d2f3fb48f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ad8946c1bed045f9a2561b4fcbc83e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a41f91fde4f4ca5d6df3f90b92c2f779 |
| publicationDate |
2013-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-102906072-A |
| titleOfInvention |
The preparation method of pyrazole carboxylic acid amide |
| abstract |
The present invention relates to a process for the preparation of compounds of formula (I) The method comprises: a) making a compound of formula (II) wherein X is chlorine or bromine, reacts with an organometallic species under an inert atmosphere to form a halophenylene of formula (X) Reaction of the halophenylene of formula X thus formed with cyclopentadiene gives (III) b) reacting III with an oxidizing agent in the presence of an inert solvent to form (IV) c) reacting IV in the presence of a Lewis acid and a hydride source to form (V) d) In the presence of an oxidizing agent, a base and an inert solvent, V is reacted to form (VI) e) Conversion of VI to (VII) in the presence of a phosphine and CCl4 or CHCl3 and f1) react VII with NH in the presence of a catalyst to form (VIII) and g) reacting VIII with a compound of formula (IX) in the presence of a base become a compound of formula I; or f2) reacting the compound of formula (VII) with a compound of formula (IXa) in the presence of a solvent, a base, a copper catalyst and at least one ligand react to form compounds of formula (I). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106414409-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106414409-B |
| priorityDate |
2010-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |