http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102902895-B

Outgoing Links

Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00
filingDate 2010-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102902895-B
titleOfInvention The screening technique of the compound of prevention and treatment human papillomavirus infectious diseases
abstract The invention discloses a kind of screening technique of the compound of prevention and treatment human papillomavirus (HPV) infection class disease, the method adopts structure-based Computer-Aided Drug Design, by human papillomavirus E1 untwist enzymatic structure based on screened, obtain suppressing the candidate compound of E1;Above-mentioned screening technique have facilitate, saves time, efficient Agilent liquid matter analyze training characteristic;The invention also discloses the compound obtained using above-mentioned screening technique, such as trovafloxacin and its derivant, Gatifloxacin and its derivant, the inhibitor of these human papillomavirus' E1 unwindases have specificity it is high, it is with strong points the characteristics of, contribute to preventing and treating human papillomaviral infection, and the disease relevant with HPV infection, the such as disease such as cervical cancer and genital wart.
priorityDate 2010-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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