http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102902895-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 |
filingDate | 2010-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102902895-B |
titleOfInvention | The screening technique of the compound of prevention and treatment human papillomavirus infectious diseases |
abstract | The invention discloses a kind of screening technique of the compound of prevention and treatment human papillomavirus (HPV) infection class disease, the method adopts structure-based Computer-Aided Drug Design, by human papillomavirus E1 untwist enzymatic structure based on screened, obtain suppressing the candidate compound of E1;Above-mentioned screening technique have facilitate, saves time, efficient Agilent liquid matter analyze training characteristic;The invention also discloses the compound obtained using above-mentioned screening technique, such as trovafloxacin and its derivant, Gatifloxacin and its derivant, the inhibitor of these human papillomavirus' E1 unwindases have specificity it is high, it is with strong points the characteristics of, contribute to preventing and treating human papillomaviral infection, and the disease relevant with HPV infection, the such as disease such as cervical cancer and genital wart. |
priorityDate | 2010-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.