http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102899288-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f65ccaa9847b1c5d528b1b69dea92789 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-39 |
filingDate | 2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37747d9d2f6922a11f8b2fc8dc703b07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a2790debb962b5f10d770771a857dee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cde569d8d736f9406c57076f740314c |
publicationDate | 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102899288-B |
titleOfInvention | Method for constructing human islet-derived pancreatic stem cell line and method for differentiation of human islet-derived pancreatic stem cell line into insulin-producing cells |
abstract | The invention discloses a method for constructing a human islet-derived pancreatic stem cell line and a method for differentiation of the human islet-derived pancreatic stem cell line into insulin-producing cells. The pancreatic stem cell line is obtained by amplifying pancreatic stem cells in human pancreatic clusters, and is a potential source for multidirectional differentiation. When induced, the pancreatic stem cell line can differentiate to form neuron-like cells, adipose-like cells, osteoblast-like cells and functional islet-like cell clusters. By transplanting the functional islet-like cell clusters into a body of a diabetic nude mouse model, the blood glucose concentration of the nude mouse model can be reduced and reach a normal level within 24 days. |
priorityDate | 2011-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 394.