http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102898542-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01B32-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
filingDate | 2012-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102898542-B |
titleOfInvention | Water-soluble fullerene and application thereof |
abstract | The invention relates to a water-soluble fullerene and an application thereof; and problems that the traditional tumor therapeutic drug has a large side effect and cannot very well suppress tumor cell proliferation can be effectively solved; and a technical scheme for solving the problems is as follows: on the basis that the original fullerene is purified, the purified fullerene reacts with an ammoniation reagent; and after an amino with stronger reaction activity is connected to the surface of the fullerene, the fullerene reacts with a hyaluronic acid, so as to generate fullerene-hyaluronic acid polymer, wherein the mass ratio of the hyaluronic acid and the fullerene is 0.18-0.25:1; and the water-soluble fullerene provided by the invention has the advantages of good physical and chemical stability, easiness for satisfying preparation conditions, rich raw material sources, low cost and small side effect and is an innovation on a tumor therapeutic drug carrier. |
priorityDate | 2012-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.