Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
filingDate |
2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2016-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-102892786-B |
titleOfInvention |
Pd-1 antibody |
abstract |
In conjunction with the humanization agonistic antibody comprising heavy chain of people PD-1, does wherein the variable domains of heavy chain comprise SEQ ID the sequence of the CDR-H1 provided in NO:1, SEQ ID the sequence of the CDR-H2 provided in NO:2 and SEQ ID the sequence of the CDR-H3 provided in NO:3, and heavy chain framework region derives from people's subgroup sequence VH4 3-1 4-30.4+JH4 (SEQ ID NO:33).The present invention also extends to the therapeutic use of antibody molecule, composition and the method for generation of described antibody molecule. |
priorityDate |
2010-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |