http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102887859-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4166 |
| filingDate | 2011-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102887859-B |
| titleOfInvention | Compound having analgesic and anti-inflammatory activity, preparation method thereof and application thereof |
| abstract | The invention discloses a compound with a general formula I, a preparation method thereof and an application thereof as an analgesic and an anti-inflammatory agent. In the general formula I, when the R1 is benzyl, the general formula I represents a compound 5a-s; and when the R1 is hydrogen, the general formula I represents a compound 6a-s. Analgesic activity of the compound provided by the invention is evaluated by using a mouse tail-flick model, and the anti-inflammatory activity of the compound is evaluated by using a xylene postauricular proinflammatory model. The experimental results show that the compound or the pharmaceutically acceptable salt thereof have excellent analgesic and anti-inflammatory activity, and can be used in the production of preparing analgesic and anti-inflammatory drugs. |
| priorityDate | 2011-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.