http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102885791-B

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filingDate 2012-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_629939d2df12dceee3a5c17454d1bc42
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publicationDate 2015-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102885791-B
titleOfInvention Method for preparing fexofenadine hydrochloride orally disintegrating tablet
abstract The invention provides a method for preparing a fexofenadine hydrochloride orally disintegrating tablet. The method comprises the following steps of: (1) providing component substances including fexofenadine hydrochloride, microcrystalline cellulose, sodium carboxymethyl starch, polyvidone and absolute ethyl alcohol in the mass ratio of 300:550:100:50:240; (2) adding the fexofenadine hydrochloride, microcrystalline cellulose, sodium carboxymethyl starch and polyvidone in the component substances, adding a mixture into a wet mixing pelletizer, and starting shearing and mixing, wherein the rotating speed of a stirring paddle is 504 revolutions per minute, the rotating speed of a pelletizing knife is 1,500 revolutions per minute, and the mixing time is 10 minutes; (3) adding absolute ethyl alcohol into a powdery mixture, and mixing continually under the condition that the rotating speed of a stirring paddle wheel is 756 revolutions per minute, the rotating speed of the pelletizing knife is 3,000 revolutions per minute to obtain wet particles; and (4) drying the obtained wet particles obtained in the step (3) in a half way.
priorityDate 2012-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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