abstract |
The present invention relates to a novel kinase inhibitor, more specifically a ROCK inhibitor, a composition containing this inhibitor, especially a medicine, and the use of the inhibitor in the treatment and prevention of diseases. In particular, the present invention relates to a novel ROCK inhibitor, a composition comprising such an inhibitor, especially a medicament, and the use of the inhibitor in the treatment and prevention of diseases. Furthermore, the invention relates to methods of treatment and the use of said compounds for the preparation of medicaments for a variety of therapeutic indications, including sexual dysfunction, inflammatory diseases, ophthalmic diseases and respiratory diseases. |