http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102876748-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7790e8f8af4261892a25e9d9a338c6c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-07 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88 |
| filingDate | 2012-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa790cd58513b91f4288ad2ad19370e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a704ba8cffb4a56cfba5ced44baa36a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aa003881e166b01a5e30910a687b6fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c74f14bb42d367870cc78684cd2b221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e145129fc1ccd43678fca16a0814074e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56247db5318c28206422f986b552b0f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3213425bce2d0596d3b6c4b18413794 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c95b06770158167a5e59d8a4dc7dd901 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ee8e3a200f4e3ea9ca7d6a7cd49b81b |
| publicationDate | 2014-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102876748-B |
| titleOfInvention | Method for preparing oligomeric hyalurate by digestion method, and oligomeric hyalurate and application thereof |
| abstract | The invention discloses a method for preparing oligomeric hyalurate by a digestion method, and the oligomeric hyalurate and an application thereof. Bacillus hyaluronidase obtained through fermental cultivation of Bacillus sp. A50 CGMCC NO.5744 is used for degrading hyaluronic acid or a salt thereof, and the method comprises the steps of preparing the hyaluronic acid or the salt thereof, enzymolysis, inactivation, filtering, settling, dewatering and drying. According to the method, the hyaluronidase produced by the Bacillus is used for degrading the hyaluronic acid or the salt thereof, and the oligomeric hyalurate is prepared through dezymotizing, alcohol or ketone settling and dewatering and drying. The method is simple to operate and mild in condition, has no destroy on the product structure and no environmental pollution, the hyaluronidase for fermentation is low in cost and is suitable for large-scale industrial production, the prepared oligomeric hyalurate has the advantages of good percutaneous absorption capability, high purity, no cytotoxicity, strong oxidation resistance and the like, and can be used in fields such as cosmetics, foods and medicines. |
| priorityDate | 2012-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 132.