| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 |
| filingDate |
2012-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a67687fb1ea4d1bf6a979c397a02f9ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63586d4811930c97fc33e14e752fdf94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a67b00a2f0f988e4938e210959f0f60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ab2eae5b84d9d647464cfa87a94d4c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bc0dfcaa0de28c89686cf9526d4c4be |
| publicationDate |
2013-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-102875695-A |
| titleOfInvention |
A glutathione-sensitive alkylated chitosan and its preparation and application |
| abstract |
The invention provides a disulfide bonded alkylated chitosan, which is obtained by modifying low molecular weight chitosan through disulfide bonded alkylation. The chitosan can form polymer micelles through self-aggregation in aqueous media, and can be taken up efficiently by cells; it can be used as a nanocarrier with excellent performance, and can realize drug delivery by utilizing high concentration of glutathione in cells. control release. The use of this carrier can be applied to the safe transport of drugs in the body; to explore the controlled release of macromolecular substances in target cells; to provide a theoretical and technical basis for the development of targeted and controlled release of drugs. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019019513-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108440512-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103424500-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104945639-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111796039-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106334195-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108117612-A |
| priorityDate |
2012-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |