http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102875421-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f0ad8476aa4a80345a4710c801c441a
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-17
filingDate 2012-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_185462ff237a26d435e3d7a8a2bcf599
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6473723b39711ad74d0e80309c82a271
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publicationDate 2014-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102875421-B
titleOfInvention Aziridine compound loop opening method based on p-nitrobenzoic acid
abstract The invention discloses an aziridine compound loop opening method based on p-nitrobenzoic acid. A tosyl activated aziridine compound is taken as a starting material, an alkali metal hydroxide is taken as a catalyst, the p-nitrobenzoic acid is taken as a nucleophilic reagent in a dimethyl sulfoxide solvent system, and loop opening reaction is carried out on the aziridine compound. The aziridine compound loop opening method based on the p-nitrobenzoic acid disclosed by the invention is simple in a reaction process, conditions are mild, the loop opening method has extensive universality, the yields of aziridine compounds in different structures are higher, and the regioselectivity is higher.
priorityDate 2012-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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