http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102872478-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8538794e1e4935e3870c2ef83e30d983 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 |
| filingDate | 2012-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ef49350da28c36fc39494c91315fd88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13d805efeba924a683689ab1eeb6526d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13e4a9d02a26aaa66af96a7bef2ea60d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc68ff71791b3a44b01c58c132511bcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd296b77a160cea59d4a6c82807df64c |
| publicationDate | 2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102872478-B |
| titleOfInvention | Method for constructing full-biological tissue engineering blood vessel |
| abstract | The invention discloses a method for constructing a full-biological tissue engineering blood vessel. The method is characterized in that an acellular tissue matrix is prepared from a sheep carotid artery; endothelial progenitor cells, smooth muscle progenitor cells and adipose-derived stem cells are respectively used as seed cells for constructing tunica intima vasorum, tunica media vasorum and tunica externa; and dynamic processes of wall shear stress, annular tension and axial tensile stress during construction of the blood vessel are realized by a bioreactor. The optimized acellular tissue matrix and optimized seed cell sources are adopted, and standard 3-D (three-dimensional) stress and dynamic regulation are realized in a construction process, so that the structure, mechanical characteristics and biological activities of the constructed tissue engineering blood vessel are close to those of a natural blood vessel. Accordingly, the method has industrial production and clinical application prospects, and a foundation is laid for the tissue engineering blood vessel to access markets. |
| priorityDate | 2012-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.