http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102871968-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66d927053feb5a5662f5ce57b1f8233d |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
filingDate | 2012-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac3a20724c07c3c4a5202d6e4047e259 |
publicationDate | 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102871968-B |
titleOfInvention | Preparation of sildenafil rhubarb hydrochloric acid salt medicine granules and preparation of suction type aerosol of gradules |
abstract | The invention provides a preparation method for sildenafil rhubarb hydrochloric acid medicine granules and a preparation method for suction type aerosol of the gradules. Sildenafil reacts with rheinic acid to form an acid salt, size-controllable medicine granules are formed by preparing the acid salt and cyclodextrin, one or more than one of polysaccharides and polylactic acids via a supercritical fluid crystallization technology, and the diameter of the prepared medicine granules is 0.5-5 microns. The medicine granules can be prepared to quantitative suction type aerosol and powder inhalations as well as other types of preparations capable of being accepted physiologically. |
priorityDate | 2012-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 154.