http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102864088-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53213eea45c1738947513195d33b262e |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-225 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-01 |
filingDate | 2011-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a6f8806ce5cded8f851c381a6c93b15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4e13a04fbbfdaaef343133ae9dddce0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7961163d7cef101c95f3496c89b54e0 |
publicationDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102864088-B |
titleOfInvention | Genetically engineering lactobacillus and application thereof |
abstract | The invention discloses a novel genetically engineering lactobacillus which is capable of decomposing a plurality of uremic toxins and is obtained by physical-chemical mutation breeding, characterized in that: the lactobacillus is obtained by carrying out directional induction on blood serums of uremic patients, and modifying the gene of the lactobacillus by dual repeated induction. The genetically engineering lactobacillus disclosed herein can be prepared into biological preparations for oral administration to plant the genetically engineering lactobacillus on intestinal mucosa for continuously decomposing uremic toxins, and the genetically engineering lactobacillus disclosed herein is used for treating uremia or chronic renal failure. Lactobacillus which is human intestinal probiotics and is planted on the inner layer of the intestinal mucosa has the functions of enhancing immunity, inhibiting pathogenic bacteria, synthesizing a plurality of vitamins, reducing cholesterol, etc. According to the invention, based on reducing a plurality of uremic toxins, the genetically engineering lactobacillus disclosed herein makes up the deficiencies of low immunity, vitamin deficiency, and fat metabolism disorder of people with chronic renal failure, and the invention provides chronic renal failure with a biological preparation for comprehensive treatment. |
priorityDate | 2011-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.