http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102861342-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71bfc04ef9fa00bef2087bb1b2497993 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e164bcc4bd54075650f89b687ea057ff |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 |
| filingDate | 2011-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_770e61d7560aff5a2e5ab9ae7a39484d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c62dcc27223d11187184e65d0364ef75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02c6b78fbe31935e1c7aac178954b9de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b987d929a7126d0d0d5151e29d746b89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d39afe4798be9805d431c360af10124 |
| publicationDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102861342-B |
| titleOfInvention | Scutellarin prodrug using cyclodextrin as carrier and preparation method for scutellarin prodrug |
| abstract | The invention discloses a scutellarin prodrug using cyclodextrin as a carrier and a preparation method for the scutellarin prodrug. Scutellarin is connected with the cyclodextrin by an ester bond formed by carboxyl in the scutellarin and hydroxyl in the cyclodextrin. Sodium salt in the scutellarin and the sulfonyl-substitutive cyclodextrin are subjected to esterification reaction in high-polarity organic solvent, and a reaction product is purified and refined to obtain the scutellarin prodrug. The scutellarin prodrug has a characteristic of being released in the rectum and the cecum of a human body, is high in bioavailability, has large quantities of hydrophilic active groups, and accordingly is good in water solubility and biocompatibility. The preparation method for the scutellarin prodrug is simple in operation, raw materials are easy to obtain, reaction conditions are mild, and the preparation method can be used for preparing scutellarin prodrugs on a large scale. |
| priorityDate | 2011-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.