http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102847168-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102847168-B |
| titleOfInvention | The design of a kind of nucleic acid vaccine PV-Fn preventing bovine mastitis and structure thereof |
| abstract | The invention belongs to microbiology, molecular biology and field of immunology, the design and the preparation that relate to the adhesin molecules FnBPA nucleic acid vaccine in staphylococcus aureus source in bovine mastitis milk sample use.By the clone to the portion gene deriving from bovine mastitis area separation strain FnBPA, analyzing its sequence and epitope, screen epitope, design construction of expression vector obtain the DNA vaccination for FnBPA molecule defined epitope.This DNA vaccination can stimulate mice to produce lasting and significant specific lymphoproliferation assay and certain humoral immunization, and the negative control group inoculated with corresponding empty carrier compares, significant difference (P ＜ 0.05).The result of challenge viral dosage shows that immune mouse can be played the effect of immunoprotection by this nucleic acid vaccine simultaneously, and this nucleic acid vaccine can safely, effectively prevent and treat mammitis of cow and drug residue free, and the preventing and treating to bovine mastitis has a good application prospect. |
| priorityDate | 2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 239.