http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102847162-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3855a0b08ee8191c2f0b1b7cadd8e4b8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2011-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9004106cd4e1c32de3cbcec068f170b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30acaf01970ba603b0468694a6553ab1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_454ee9c1a78ffa7aef08f3f54d3e639a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0867c2358fd935a86033b6000215487c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_131a416cc5958c5cf79945b4cbc5f80a |
| publicationDate | 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102847162-B |
| titleOfInvention | Method for preparation of active immunoadsorbent carrier |
| abstract | The present invention relates to a method for preparation of an active immunoadsorbent carrier. The active immunoadsorbent carrier is N, O-succinyl ethylene glycol chitosan prepared with glycol chitosan as monomer with succinic anhydride as acylating agent through acylation of water-soluble glycol chitosan. The active immunoadsorbent carrier is an amphipathic cationic polymer, has super high bioadhesive and adsorption promoting characteristic, and can easily combine with a negatively charged peptide drugs, genes, and vaccines. N, O-succinyl ethylene glycol chitosan polymer with a particular degree of substitution can be synthesized by controlling reaction conditions and feeding proportion. The polymer gel can be used as carrier of rheumatoid arthritis immunoadsorbent with adsorption clearance rate up to 60.9%, 63.5%, and 48.0%. N, O-succinyl ethylene glycol chitosan polymer gel can be used as a carrier to prepare immunosorbent, and has high selectivity, high adsorption efficiency, no adsorption of non-objective substance, no coagulation, no hemolysis, good blood compatibility, easy sterilization, good mechanical strength, and easy activation. |
| priorityDate | 2011-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.