http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102846595-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 |
| filingDate | 2012-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dcf9ce9cab37e30a6c449fdce7711fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d755abca0daacdfe3e403658d8aff709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e50d71fd5bcafa2c4ec0bfceaffb09ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f526b9fcd0d3a1ef25dee444caaf275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7c2714ec0d7ecd6da90c2dc09d2eb9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daa1ea209a75c3494fbc501a085c6b8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e131e335e6c482910679a19bf94a9b0b |
| publicationDate | 2013-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102846595-B |
| titleOfInvention | Application of flavonoid compound WX-03 in relaxation of vascular smooth muscles |
| abstract | The invention relates to the technical field of medicines, specifically to application of a flavonoid compound WX-03 (7-[2-(dimethylamino)ethyoxy]flavone) in relaxation of vascular smooth muscles. Research shows that: WX-03 can reduce the tension of domestic rabbit isolated vascular smooth muscles, can relax vascular smooth muscle contraction caused by spasm inducing agents norepinephrine and potassium chloride, and the blood vessel relaxation effect of WX-03 is likely to have nothing to do with ATP sensitive potassium channels; and the blood vessel relaxation effect of WX-03 is related to calcium channel inhibition. The minimum effect taking concentration is 3*10<-5>mol/L. The 7-[2-(dimethylamino)ethyoxy]flavone has guiding significance on treating hypertension so as to reduce the damage on target organs, and reducing cerebral stroke, angina pectoris, myocardial infarction, heart failure, renal failure and other serious complications and other diseases. |
| priorityDate | 2012-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.