Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e74277852f1aae0a3ff13f59a65456d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-20222 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-47 |
filingDate |
2012-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89567f859d9c718f85ea1f395f3124f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd89f83329c62689292f26f675f129ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e32aa4cba5857e08e8e71141d4064053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31f64748521e57b1bac6e5c1d765e22a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27e17b774266a6c6f53b74271f458696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa015d8a96086b2ee9a63772991e57d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3726659097654fcb7710f05fda89c405 |
publicationDate |
2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-102838663-B |
titleOfInvention |
Viromembrane protein with site-specific mutagenesis and site-specific decoration, preparation method and applications of viromembrane protein |
abstract |
The invention discloses viromembrane protein with site-specific mutagenesis and site-specific decoration, a preparation method and applications of the viromembrane protein. Amber codon TAG is introduced to the specific site of envelope protein G (VSV G) gene of vesicular stomatitis virus, unnatural amino acid DiZPK with photo-crosslinking property is introduced to the specific site of VSV G by utilizing the orthorhombic aminoacyl-tRNA synthetase-tRNA through site-specific mutagenesis. In the interaction process of virus and host cells, the DiZPK photo-crosslinking reaction is triggered by 365nm ultraviolet light, the covalent bond is formed between the VSV G and interacting protein, the interaction dissociation can be avoided, and the powerful measure is provided for the research of the interaction of the virus and protein of the host cells. |
priorityDate |
2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |