http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102838621-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a6ce470860f620e859cb41c17ce70b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e11e2853eaf85bfdf259fb50aa33a14 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 |
| filingDate | 2011-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa8305f52dd44c621ef1881cabb08310 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_635ad3b5ef4920e20f04d95b10e09278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_def1e5cedc3d8859ad7cb5415c9b1287 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6699e5aadce1d5d26b09ee16ebda8593 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d64da062464dbd04a52bc85a3e6632ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f999baa6ad3ebd79ad217ccc5a7aba94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2a55c8daffd7c416c754fd478055e7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_196cbe85bf052ad13b35201e1b466cbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d30d20a112416669246a75c66d38699 |
| publicationDate | 2014-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102838621-B |
| titleOfInvention | (6R,7R)-3-methyl-7-[alpha-(N,N'-diisopropyl amidine thio)-acetylamino]-8-oxo-5-thia-1-azabicyclo[4,2,0]-oct-2-alkene-2-formic betaine crystals |
| abstract | The invention relates to (6R,7R)-3-methyl-7-[alpha-(N,N'-diisopropyl amidine thio)-acetylamino]-8-oxo-5-thia-1-azabicyclo[4,2,0]-oct-2-alkene-2-formic betaine, crystals thereof, and preparation method and application thereof. According to the invention, 7-ADCA and bromoacetyl bromide are subjected to a reaction, such that an intermediate A, which is 7-bromo acetylamino-3-methyl-8-oxo-5-thia-1-azabicyclo [4.2.0] oct-2- alkene-2-formic acid, is obtained; the intermediate A is subjected to a reaction with N'N-diisopropyl thiourea, such that the compound provided by the invention is obtained. The compound is further refined, such that the crystals of the compound with high purity and good stability are prepared. The compound provided by the invention has antibacterial effects against escherichia coli, staphylococcus aureus, streptococcus pneumoniae, Hay enterococci, enterococcus faecalis, and the like. Especially, the compound has a high inhibiting activity against streptococcus pneumoniae. The compound is a potential antimicrobial medicine. |
| priorityDate | 2011-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.