http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102838597-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_217f2be73fd6be0be36dd55803d3bec5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2012-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bca49a007d28163adf9c3b900bd9914f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5dfcad5aa77f78301ef3267ef96edfe |
| publicationDate | 2014-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102838597-B |
| titleOfInvention | Preparation method of heteroaromatic iminazole [1,2-Alpha]pyridine compounds |
| abstract | The invention relates to a preparation method of heteroaromatic iminazole [1,2-Alpha]pyridine compounds. The method comprises the steps that under the existence of univalent silver salt, 2-amino pyridine compounds and acetylene compounds are dissolved in organic solvents to be reacted for 10 to 24 hours at the reacting temperature of 100 to 130 DEG C, and then the compounds are separated and purified to prepare the heteroaromatic iminazole [1,2-Alpha]pyridine compounds. The reacting compounds used in the method of the utility model can be simply prepared at a low cost, the reacting condition is very simple, atom economy is very high, and the oxidation cyclization reaction of the 2-amino pyridine compounds and the acetylene compounds can be realized in a highly selective mode, so as to prepare the heteroaromatic iminazole [1,2-Alpha]pyridine compounds. The method can prepare the prodrug of a drug with adone zoli pyridine simply, and the drug is widely applied to treating gastric ulcers and gastroesophageal reflux diseases. The preparation method provided by the invention has great application potential for synthetizing medicine, natural products and the like. |
| priorityDate | 2012-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.