http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102836133-B

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filingDate 2012-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e104c61a6c5437fc3fae377974ed25ac
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publicationDate 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102836133-B
titleOfInvention Sodium aescinate freeze-dried powder injection and preparation method thereof
abstract The invention discloses a sodium aescinate freeze-dried powder injection which has single preparation component and high stability and is free from irritation and a preparation method thereof. The freeze-dried powder injection comprises sodium aescinate serving as a major agent, tert-butyl alcohol serving as a freeze-drying protective additive and water for injection in the mass ratio of 1:(50-300):100. The preparation method comprises the following steps of: dissolving sodium aescinate into tert-butyl alcohol; stirring for dissolving; adding water for injection, mixing and stirring to obtain a clear and bright solution; and performing adsorption decarburization, filtration sterilization and split charging freeze drying to obtain a sodium aescinate freeze-dried powder injection. The sodium aescinate freeze-dried powder injection prepared with the method disclosed by the invention can be produced efficiently on an industrial scale by adopting the conventional process equipment; and moreover, a process is simple, a tert-butyl alcohol-water cosolvent can be recycled, preparation cost is saved, and discharge of waste is reduced.
priorityDate 2012-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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