| abstract |
A macrocyclic heterocyclic compound for inhibiting hepatitis C virus and its preparation and application. The invention discloses a class of macrocyclic heterocyclic compounds represented by formulas Ia and Ib, its intermediates, preparation method and application. The macrocyclic heterocyclic compound of the present invention has better inhibitory activity on hepatitis C virus, can be effectively used for treating hepatitis C virus infection, and has better hepatitis C virus inhibitory selectivity and very low toxic and side effects . |