| abstract |
The invention provides thienopyrazole derivatives inhibiting PDE 7 selectively, and therefore, enhancing cellular cAMP level. Consequently, the compound is useful for treating various kinds of disease such as allergic diseases, inflammatory diseases or immunologic diseases. The compound is thienopyrazole compound represented by the following formula (I): [wherein, especially, R1 is a cyclohexyl, a cycloheptyl group or a tetrahydropyranyl group; R2 is methyl; R3 is a hydrogen atom; and R4 is a group: -CONR5R6 (in which any one of R5 and R6 is a hydrogen atom)]. |