http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102818867-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e05922083f754c84badc599a8923021 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2012-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94dacd0e51e6d98636ebbc57891b45e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ff355ce0916c19de50b62658aac8f9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90aaa197465a7755abe9effd9158e16a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d2d46a8fe69a91c0943facd02af1cc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c266c6bfaa4902dc94f82a01419a1689 |
| publicationDate | 2014-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102818867-B |
| titleOfInvention | Quality control method for ribonucleic acid II for injection |
| abstract | The invention discloses a quality control method for ribonucleic acid II for injection. The method comprises the following steps that the nucleic acid enzyme hydrolysis solution of a substance to be measured is subjected to high-performance liquid chromatogram analysis, an adopted chromatographic column is an Agilent ZORBAX SB-AQC18 chromatographic column, and a flowing phase is a mixture of a formic acid solution and an acetonitrile solution; after the analysis, if the substance to be measured is determined to contain five substances as follows: cytidylate, uridine monophosphate, guanine nucleotide, guanosine and adenosine, the substance to be measured is the ribonucleic acid II for injection or is the ribonucleic acid II for injection as a candidate; and if not, the substance to be measured is not the ribonucleic acid II for injection or is not the ribonucleic acid II for injection as the candidate. A high-performance liquid chromatographic technique is utilized, and the strong-specificity quality control method for the ribonucleic acid II for injection is established. The method has important meanings on increasing the technological content of the medicine, increasing the safety and effectiveness, reducing the cost, enlarging the production scale, increasing the market occupancy, and going forward to the international market. |
| priorityDate | 2012-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.