http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102807557-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65682d3e437c225d79b93953b4b26392 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D339-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D339-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-385 |
filingDate | 2012-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aefbe0e0bc77f61a64563364b7f3ca81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccdd94c1cbe7c6e064f0bea9a09581e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29f6a49135387091318739f3df898481 |
publicationDate | 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102807557-B |
titleOfInvention | 3H-1,2-dithio-cyclopentene-3-thioketone compound and application thereof |
abstract | The invention relates to the field of medicaments, and in particular relates to a 3H-1,2-dithio-cyclopentene-3-thioketone compound and an application thereof. The 3H-1,2-dithio-cyclopentene-3-thioketone compound disclosed by the invention has a structure shown in a formula I or a formula II and is a compound with a completely-new structure. Proved by experiments, the 3H-1,2-dithio-cyclopentene-3-thioketone compound has a direct protection role on neurons on a cell model, and can obviously restrain excessive inflammatory responses of inflammatory cells in the cerebrum; and by using 3H-1,2-dithio-cyclopentene-3-thioketone, focal cerebral ischemia cerebral infarction volume of a mouse can be obviously reduced in an animal model. Therefore, the invention provides the 3H-1,2-dithio-cyclopentene-3-thioketone compound and the application of acceptable slat of the 3H-1,2-dithio-cyclopentene-3-thioketone compound on the pharmacy aspect to the preparation of medicaments for preventing or treating a cerebral apoplexy disease. |
priorityDate | 2012-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 202.