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filingDate 2011-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33e7126a92ad662638d48581e685d613
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publicationDate 2013-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102805747-B
titleOfInvention Use of 2-(4-morpholinoaniline)-6-cyclohexyl aminopurine and pharmaceutically acceptable salt or derivative of 2-(4-morpholinoaniline)-6-cyclohexyl aminopurine in pharmacy
abstract The invention provides a new use of 2-(4-morpholinoaniline)-6-cyclohexyl aminopurine and pharmaceutically acceptable salt or derivative of the 2-(4-morpholinoaniline)-6-cyclohexyl aminopurine. The chemical compound can inhibit the synthesis of activated hepatic stellate cells, the synthesis and expression of superficial collagen and other extracellular matrix proteins, including MMPs (matrix metalloproteinases) and TIMPs (tissue inhibitor of matrix metalloproteinases), and the hepatic fibrosis; the chemical compound can inhibit the synthesis and expression of the collagen in human bodies, so as to reverse and treat hepatitis and the hepatic fibrosis; and the chemical compound can be used independently or in conjunction with targeted molecules or carriers, including vitamin A-coupled liposome, so as to be prepared into drugs for treating or preventing the infectious hepatitis, non-infectious hepatitis, hepatic injury, cirrhosis, liver cancers and hepatic fibrosis, and protecting or improving liver functions.
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