http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102793915-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a643fe7f9a0686b0402d8e5282a87e4 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-10 |
| filingDate | 2012-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12d7c7ce63ccf41c738353b0ba58d28c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b4fa6e84ff7b069bd27161d074de528 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df16d10811a09c6445e6aff0b91a96b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_254d41eec01746f841b9c0ae14005a56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91faba6844612258a19a426c5b665bb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc78ef67f67ab22c15ff576bdfc2261d |
| publicationDate | 2013-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102793915-B |
| titleOfInvention | Production method of acellular pertussis vaccine |
| abstract | The invention discloses a production method of an acellular pertussis vaccine. The production method comprises the following steps of: fermenting and purifying a Fha bordetella pertussis genetic engineering strain in which pt gene is knocked out to obtain an antigen component fha; fermenting and purifying the Pt bordetella pertussis genetic engineering strain in which fha gene is knocked out to obtain an antigen component pt; fermenting and purifying Prn bordetella pertussis genetic engineering strain in which fha gene is knocked out to obtain an antigen component prn; and preparing the acellular pertussis vaccine from the antigen components fha, pt and prn. According to the method, high-efficiency expression of a single target antigen can be realized, so that the growing speed of the bordetella pertussis genetic engineering strain is remarkably accelerated, and the production time and production cost can be reduced. |
| priorityDate | 2012-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.