| abstract |
The present invention discloses including R-G-sulfoalanine (ie R-G-NH-CH( CH2 - SO3H )COOH or Arg-Gly-NH-CH( CH2 - SO3H )COOH) and derivatives thereof (including pharmaceutically acceptable salts, hydrates, stereoisomers, multimers, cyclic forms, linear forms, drug conjugates, prodrugs and derivatives thereof). Also disclosed are methods of making and using such compounds, including methods of inhibiting cell adhesion to the RGD binding site or delivering other diagnostic or therapeutic agents to the RGD binding site in a human or animal subject. |