http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102787174-B

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filingDate 2012-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2013-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102787174-B
titleOfInvention Kit for morbidity-related tumor suppressor gene epigenetic mutation detection of gastrointestinal neoplasms and application thereof
abstract The invention relates to a kit for morbidity-related tumor suppressor gene epigenetic mutation detection of gastrointestinal neoplasms and application thereof. The kit mainly comprises 25 pairs of gastrointestinal neoplasm morbidity-related tumor suppressor gene promotor region CpG-island amplification and sequencing primers of 9 kinds and a polymerase chain reaction (PCR) amplification reagent. Through a PCR amplification product obtained through the kit, a gene CpG-island methylation state can be analyzed through the methods of methylation specific PCR (MSP), combined bisulphite-restrictionanalysis (COBRA) or bisulfite sequencing PCR (BSP) and the like. The kit has the efficient effect of detecting CpG-island methylation and is used for the morbidity-related tumor suppressor gene epigenetic mutation detection of the gastrointestinal neoplasms.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105969896-A
priorityDate 2012-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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