abstract |
The present invention relates to heterocyclic compounds including all stereoisomeric and tautomeric forms thereof; and pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutically acceptable isomers thereof. The present invention also relates to the preparation method of the heterocyclic compound and the pharmaceutical composition containing it. The compounds and their pharmaceutical compositions are useful in the prevention and treatment of diseases or disorders modulated by diacylglycerol acyltransferases (DGATs), especially DGAT1. The present invention further provides methods of treating said diseases or disorders by administering to a mammal in need thereof a therapeutically effective amount of said compounds and their pharmaceutical compositions. |