http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102775496-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
filingDate | 2011-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102775496-B |
titleOfInvention | Composite medicine for targeted elimination of HIV/SIV |
abstract | The invention relates to composite medicine for targeted elimination of HIV/SIV. Specifically, the invention relates to a fusion protein, which is composed of human cytokine polypeptide IL2, IL7, DNA binding protein SON2 rich in positive amino acids, as well as a co-receptor polypeptide CXCR4 able to achieve specific binding with gp120 and/or gp41 and neutralization of a free HIV virus, and serves as a non-viral vector. The non-viral vector fusion protein and a restrictive toxin gene expression recombinant DNA can be assembled to form the composite medicine. The invention also relates to application of the fusion protein and the composite medicine in elimination of HIV in AIDS (acquired immune deficiency syndrome) patients. |
priorityDate | 2011-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 228.