http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102775389-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9353da21ba23e86e687a465920a68849 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 |
| filingDate | 2012-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c6d6a93a61a698fd6fca89d028c98ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0645529a479c283eb7b9ce189d9a244 |
| publicationDate | 2014-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102775389-B |
| titleOfInvention | Preparation method of N-substituted-4-(7-chloro-quinoline -4-amino)-benzamide derivatives, and application thereof |
| abstract | The invention discloses a preparation method of N-substituted-4-(7-chloro-quinoline-4-amino)-benzamide derivatives; the preparation method comprises the steps of: a, taking para aminobenzoic acid and 4, 7-dichloro-quinoline as raw materials, and carrying out reflux reaction to obtain IV 4-(7-chloro-quinoline-4-amino)-benzoic acid; b, leading the obtained IV 4-(7-chloro-quinoline -4-amino)- benzoic acid to have reflux reaction with sulfoxide chloride to obtain 4-(7-chloro-quinoline-4-amino)- benzoyl chloride; and c, adding 2-(5-amino-2-methylaniline)-4-(4-pyridina) pyridine into the obtained 4-(7-chloro-quinoline-4-amino)- benzoyl chloride for complete reaction, and carrying out recrystallization to obtain the N-substituted-4-(7-chloro-quinoline-4-amino)-benzamide derivatives. |
| priorityDate | 2012-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.