Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aaaaf4049c38c48aea4f1320fa64fb20 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-93 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
filingDate |
2012-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a6f2f09b92fb129f0a834cfc9b1f588 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62962e6e5dd572e9a1d68bb3a8fe61bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab81faa58124f3f4b33d977ebf98605b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20683d1d2596a0386325e06cccd5a99c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1230ac9992ff47c42b38aa4347eaa83a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_976ee18ec01e245c72ce25ce365113d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c63d4d3450881ee59918f71c2ffd8439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_458e1becbd7ff147973a3d231aa6e310 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1924e6037d18a1710f8ffda855a9b32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7992d87ee8ccc92f76f2778ec2d8510c |
publicationDate |
2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-102766207-B |
titleOfInvention |
Bactrian camel heavy-chain (HC) variable-domain antibody resisting porcine circovirus 2 as well as preparation method and application thereof |
abstract |
The invention discloses a bactrian camel heavy-chain (HC) variable-domain antibody resisting a porcine circovirus 2 as well as a preparation method and an application thereof, and belongs to the field of a biotechnology. A PCV2 (Porcine Circovirus Virus) inactivated vaccine immunized bactrian camel is firstly utilized and a phage display technology is utilized to establish a PCV2 immune VHH antibody base; and a high-specificity variable domain antibody of heavy chains of HCAbs (VHH) which has a good affinity with the PCV, particularly a PCV2 virus antigen; and the antibody disclosed by the invention has an amino acid sequence shown as SEQ (sequence) ID NO.1 or an amino acid sequence which is shown as SEQ ID NO.2 and has the sequence isogeny being more than 95%. The PCV2 heavy-chain variable-domain antibody disclosed by the invention has the very important meanings on researching porcine circovirus, particularly researching a porcine circovirus 2-type infection mechanism and establishing rapid antigen detection with high sensitivity and specificity or diagnosing a reagent. |
priorityDate |
2012-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |