http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102759596-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-89
filingDate 2012-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00c82fc7cb32b045966695cd6769e335
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b77332c9b0d39efff4434549cedfd621
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85cfbee20a5b25f2a80e066620c4729c
publicationDate 2014-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102759596-B
titleOfInvention Method for detecting low-molecular-weight heparin by combining ion pair reversed phase chronmatogaphy and mass spectrum
abstract The invention relates to a method for detecting low-molecular-weight heparin by combining ion pair reversed phase chronmatogaphy and mass spectrum. The method comprises the steps of: detecting all compositions of low-molecular-weight heparin by combining ion pair reversed phase chronmatogaphy and high-resolution mass spectrum, separating main compositions from a sample through the ion pair reversed phase chronmatogaphy, obtaining precise molecular weight by the high-resolution mass spectrum, and calculating information of a carbohydrate chain sequence, including structures of two ends, length of a carbohydrate chain and substitution number of ethanoyl and sulfate, thus carrying out fine surface features on the low-molecular-weight heparin. The method has great practical values on improving the heparin detection level and ensuring drug safety.
priorityDate 2012-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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